The GLP-1 Library Every Guide, By Question
Thirty-four guides, each one built on published trial data and cited by PMID. Grouped by the question that brought you here rather than by publication date.
Start Here
What the drugs are, what the trials actually showed, and what to expect month by month.
What Are GLP-1 Medications? The Complete Evidence-Based Guide
A plain-language, PubMed-sourced guide to GLP-1 receptor agonists — what they are, how they work, the major drugs in the class, and what the trial…
Read ->Ozempic, Wegovy, Mounjaro, Zepbound: Four Names, Two Drugs
The four brand names are two molecules with two approvals each. What the head-to-head trial found, and the question the comparison does not answer.
Read ->The GLP-1 Weight Loss Timeline: What Happens, And When
What to expect month by month on GLP-1 medications — the dose escalation period, when loss is fastest, when it slows, and what the trial curves…
Read ->How Much Weight Can You Lose on GLP-1 Medications?
STEP-1 and SURMOUNT-1 trial results translated into realistic expectations for Ozempic, Wegovy, Mounjaro and Zepbound — average, range, timeline, and…
Read ->GLP-1 Medications and Metabolic Health: The Full Picture
What the trial evidence shows about GLP-1 medications beyond weight loss — diabetes, cardiovascular risk, fatty liver, sleep apnea and blood pressure…
Read ->The SELECT Trial: What A 20% Risk Reduction Actually Means
SELECT enrolled 17,604 people and reported a 20% reduction in major cardiovascular events. Here is the absolute number behind that percentage, and…
Read ->Side Effects
The common ones, why they happen, and which are worth a call to a doctor.
GLP-1 Side Effects: The Complete Evidence-Based Guide
Every documented GLP-1 side effect ranked by frequency and severity, sourced to meta-analyses covering over 100,000 trial participants — Ozempic,…
Read ->Nausea On GLP-1 Medications: Why It Happens And What Helps
Why nausea is the most common GLP-1 side effect, when it typically settles, and the evidence-based strategies that reduce it.
Read ->Constipation On GLP-1 Medications: How Common, And What Works
How often constipation happens on Ozempic, Wegovy, Mounjaro or Zepbound, why the mechanism causes it, and the strategies that follow from that…
Read ->Diarrhoea On GLP-1: Normal, Or Not?
How often diarrhoea happens on GLP-1 medications, why the same drug causes both diarrhoea and constipation, and the point at which it needs medical…
Read ->Fatigue On GLP-1 Medications: Why It Happens
How common fatigue is on Ozempic, Wegovy, Mounjaro or Zepbound, the four separate causes behind it, and which ones you can do something about.
Read ->Does GLP-1 Cause Hair Loss? What The Cohort Data Shows
Hair loss on Ozempic, Wegovy or Mounjaro — what a 547,993-person cohort found, whether it is the drug or the weight loss, and whether it grows back.
Read ->“Ozempic Face”: What The Review Actually Found
Facial volume loss on GLP-1 medications — which areas change, and why a systematic review concluded it is rapid weight loss rather than the drug.
Read ->Gallstones And GLP-1 Medications: What The Meta-Analyses Show
Quantified gallstone risk on GLP-1 medications, why rapid weight loss raises it independently, and the symptoms that need urgent assessment.
Read ->GLP-1 And Pancreatitis: Separating Signal From Noise
What the cohort data actually shows about pancreatitis risk on GLP-1 medications, why the confidence intervals are so wide, and the symptoms that nee…
Read ->GLP-1 And Sleep Apnea: What The Trial Showed
Tirzepatide cut apnea events by roughly two thirds in two randomised trials. What that means, what it does not mean, and why nobody in the trial was…
Read ->GLP-1 And Fatty Liver: The Placebo Column
Semaglutide resolved steatohepatitis in 62.9% of patients in the ESSENCE trial. It also resolved in 34.3% of the placebo group.
Read ->Eating On A Suppressed Appetite
The hardest practical problem: hitting a protein target when you cannot eat much.
How Much Protein Do You Need on GLP-1 Medications?
The joint-society protein target for people on Ozempic, Wegovy, Mounjaro or Zepbound — how much, per meal, and how to hit it on a suppressed appetite.
Read ->Best Protein Sources When You Can Only Eat A Little
Protein density ranked — the foods that deliver the most protein per bite when appetite is suppressed, and the ones that waste the room you have.
Read ->What to Eat on GLP-1 Medications: The Complete Nutrition Guide
A protein-first, evidence-based eating framework for Ozempic, Wegovy, Mounjaro and Zepbound — built for small appetites, GI tolerance, and hitting…
Read ->Small Meals Or Three Meals On GLP-1 Medications?
Whether to eat more frequent small meals or stick to three on a suppressed appetite — and why the protein target decides it rather than metabolism.
Read ->Fibre On GLP-1 Medications: More Is Not Automatically Better
Why fibre matters more on GLP-1 medications and why adding it wrongly makes things worse — the order to change things in, and the types that behave…
Read ->Hydration And Electrolytes On GLP-1 Medications
Why fluid intake falls on GLP-1 medications without you noticing, when electrolytes actually matter, and the warning signs that need medical…
Read ->Micronutrient Deficiency Risk On GLP-1 Medications
Eating substantially less means eating fewer micronutrients. Which ones are most at risk on GLP-1 medications, what to get checked, and when a…
Read ->Alcohol And GLP-1 Medications: What The Evidence Shows
A randomised trial tested semaglutide on alcohol consumption. What it found, what it did not test, and the practical considerations for drinking on a…
Read ->Air Fryer Cooking For GLP-1 Users
Why an air fryer suits protein-first cooking on a suppressed appetite — portion sizing, texture when food is unappealing, and how to batch a week.
Read ->The Protein Target Without Meat, On A GLP-1
Plant protein is not inferior in the way it is usually described — the meta-analysis found no difference in absolute lean mass.
Read ->Muscle And Training
Roughly a quarter to a third of weight lost is lean mass. This is the part you can change.
GLP-1 And Muscle Loss: How Much, And How To Stop It
What body-composition trials actually show about lean mass loss on Ozempic, Wegovy, Mounjaro and Zepbound, and the two evidence-backed ways to…
Read ->Resistance Training On GLP-1: The Other Half Of The Result
What a year-long randomised trial found when exercise was added to a GLP-1 medication — and why training is one of only two interventions with…
Read ->The Best Exercise Routine for GLP-1 Users
A weekly training template balancing strength, cardio and recovery for people on Ozempic, Wegovy, Mounjaro or Zepbound — with beginner modifications…
Read ->Cardio Or Strength Training On GLP-1 Medications?
Which type of exercise matters more during GLP-1 weight loss, what the randomised trial found, and how to split limited time and energy between them.
Read ->How To Strength-Train On Low Energy And No Appetite
Training when appetite is suppressed and energy is low — what to cut, what to keep, and how to make sessions productive on a restricted intake.
Read ->GLP-1 And Sarcopenia Risk In Older Adults
Why older adults face a different risk calculation on GLP-1 medications, what the body-composition data shows, and the assessment guidance says to do…
Read ->Creatine On GLP-1 Medications: Does It Help Protect Muscle?
What the creatine evidence says about lean mass, whether it applies to GLP-1 users, and the honest answer about what has and has not been tested.
Read ->HMB For Lean Mass: Who It Actually Helps
What the HMB meta-analysis found — and the subgroup result that decides whether it is worth your money on a GLP-1 medication.
Read ->GLP-1 Medications And Menopause: What The Small Studies Show
Does menopause change how these medications work? Two studies say something useful about hormone therapy and about lean mass — and both are small…
Read ->Plateaus And What Comes After
Why loss slows, what the discontinuation data shows, and how maintenance differs.
Why Your GLP-1 Weight Loss Stalled: The Plateau, Explained
Why weight loss slows on Ozempic, Wegovy or Mounjaro — what the trial curves show, what a plateau actually means, and what is and is not worth…
Read ->Maintaining Weight Loss After GLP-1 Therapy
What the discontinuation data shows, why maintenance is a different problem from loss, and what the evidence supports for keeping the weight off.
Read ->What Happens To Your Weight When You Stop GLP-1 Medications?
Pooled data on weight regain after stopping Ozempic, Wegovy, Mounjaro or Zepbound — how much comes back, how fast, and why clinicians call it…
Read ->Not Losing Weight On A GLP-1? You Are In The Trials Too
13.6% of the semaglutide group in STEP-1 did not reach 5% weight loss. Half did not reach 15%. The averages you have been comparing yourself to hide…
Read ->Supplements, Tools And Measurement
What has evidence behind it, what to measure, and what to ignore.
Best Supplements for GLP-1 Users: An Evidence-Based Ranking
Which supplements actually have evidence behind them for Ozempic, Wegovy, Mounjaro and Zepbound users — ranked by evidence tier, including what to…
Read ->Measuring Body Composition At Home
Smart scales, waist tape and what each one is good for, including the honest limits of home body-fat readings.
Read ->The High-Protein Kitchen: What You Actually Need
The complete guide to equipping a kitchen for protein-first eating — what to buy, in what order, and the four things you can skip entirely.
Read ->GLP-1 Full Guide — The Book
GLP-1 Full Guide: 151 pages on protecting muscle while you lose fat, with 19 peer-reviewed references cited by PMID and DOI.
Read ->Free
No purchase, no catch — the reference material we would want ourselves.
Free: The GLP-1 Muscle & Protein Guide
A free 7-page guide to protecting muscle on GLP-1 medications — the protein target by bodyweight, the training that matters, and what the trials…
Read ->Free High-Protein Air Fryer Recipe Ebook
Download a free high-protein air fryer recipe ebook with practical meals for fat loss, muscle gain and meal prep.
Read ->Where treatment actually starts
Every page in this section covers the evidence. None of it substitutes for a consultation.
Hims is a US telehealth service that connects you with licensed providers for an online consultation. If a provider prescribes treatment, it is fulfilled through FDA-regulated pharmacies. Whether anything is prescribed is their decision, not ours and not yours.
The Iron Verdict earns a commission if you subscribe. It changes nothing on this page. The trade-offs, the side effects and the numbers that do not flatter the drugs are all still here, and they stay here.
See what Hims offers →Available in the United States only. This is not medical advice, and nothing here is a recommendation to take any medication.